Towards chitosan-amorphous calcium phosphate nanocomposite: Co-precipitation induced by spray drying

Towards chitosan-amorphous calcium phosphate nanocomposite: Co-precipitation induced by spray drying

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This article reports the successful one-step synthesis of two micron-sized composite powders consisting of chitosan and amorphous calcium phosphate.These composite materials are prepared by spray drying of a solution containing chitosan best 6.7 powerstroke intercooler pipe upgrade and calcium phosphate precursors.The co-precipitation of chitosan and calcium phosphate precursors during the process induces a highly homogeneous distribution of the phases.The mineral phase identified as spherical nanoparticles dispersed in chitosan showed no chemical bonding with the polymer.

As demonstrated by electron microscopy, small angle X-ray scattering and spectroscopies, variation in chitosan concentrations significantly influences the sensationnel brielle size and spatial distribution of the mineral phase.These results present a promising approach for the preparation of chitosan/amorphous calcium phosphate composite powders with controlled and tunable properties with potential applications in the field of biomaterial engineering such as bone substitutes.